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RACK protein : ウィキペディア英語版 | RACK protein
RACK is an acronym for Receptor for Activated C-Kinase and is responsible for the binding of active forms of the protein kinase C (PKC) family of enzymes. See also RICK protein, Receptor for Inactive C-Kinase. There are different RACKs for different isoforms of PKC, which thus mediate differential subcellular targeting of the isoforms. Inactive forms of PKC occlude the RACK binding site with a pseudo-RACK peptide sequence RACKs share 47% identity with the beta subunit of G proteins. RACKs represent one of the many ways in which a cell can use signalling complexes to manipulate the specificity of interactions within intracellular signalling cascades.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「RACK protein」の詳細全文を読む
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